Congenital insensitivity to pain with anhidrosis (CIPA Disease) | What is CIPA Disease

 Overview: 

Congenital Insensitivity to pain with anhidrosis (CIPA). It is a disease in which patient cannot feel any pain and cannot sense any temperature. There is no sweating in his body (anhidrosis). It is also called hereditary sensory and autonomic neuropathy type IV. It's symptoms appear in early age, after birth and during childhood.

It is actually a genetic disease. It cause due to genetic mutation.

Proper medical care can lead a safe life and person can reach his adult life. 

Mostly people died at the age of 3 due to many infections and injuries on their body. They can't able to detect any symptoms because they cannot feel pain. It is very difficult for that person to live a long life.

A CIPA patient can live approximately 25 years old. This disease slowly slowly destroy internal body. 

People with an inability to feel pain and temperature often hurt themselves without realizing it. They might accidentally bite their tongue, lips, or fingers, and this could even lead to body parts spontaneously getting cut off. These individuals also heal slowly from injuries, and repeated injuries can cause chronic bone infections. Since they don't sweat properly, they can have very high fevers and seizures due to the heat. People with this condition might have tough skin on their palms, weird-shaped nails, and patches on their head without hair. Some might be hyperactive or emotionally unstable, and many might have learning challenges. Though they might have weak muscles when young, it often improves as they grow up. 

It's other names:

CIPA

Hereditary insensitivity to pain with anhidrosis

Hereditary sensory and autonomic neuropathy type IV

Hereditary sensory and autonomic neuropathy, type 4

HSAN type IV

HSAN4

This disease cannot be cured.